uesto sito fornisce informazioni su palmitoylethanolamide. PEA è disponibile come PeaPure, Normast, Pelvilen e attraverso gli altri nomi commerciali. Normast in Italia attraverso la farmacia e ottenere PeaPure è realizzato nei Paesi Bassi e in tutto il mondo come un supplemento inviato.

I neutraceutici PeaPure® e Normast®, sia palmitoiletanolamide antidolorifico naturale (PEA) contengono, aprendo la strada a un nuovo metodo naturale di trattamento del dolore cronico. Entrambi i prodotti sono realizzati secondo i più alti standard (GMP). Perché PEA nei Paesi Bassi solo dal 2010, e abbiamo anche molte domande per telefono, ecco un elenco di domande e risposte. Anche domande e commenti da parte di persone su Fori di discussione su PEA parlare, abbiamo elaborato.

Fine anno del 2012 nei Paesi Bassi, sono decine di migliaia di pazienti trattati con PEA. Non ci sono effetti collaterali significativi segnalati. PEA può essere senza problemi, oltre a prendere altri farmaci e medicinali.

De invalshoek die we de laatste jaren ontwikkeld hebben, 'iedereen heeft recht op pijnstilling zonder bijwerkingen' krijgt ook in het buitenland steeds meer resonantie. De voorzitter van Stichting IOCOB was gast op een anderhalfuur durend interview over de behandeling van bekkenpijnen. De 'show' heet The Pelvic Messenger en werd door vele duizenden patienten beluisterd. Het interview is te horen op de link hieronder.

The Pelvic Messenger 

The show "The Pelvic Messenger" has been created as a live talk podcast which stems from the website PelvicMessenger. I, Jessica Mariotti Tomsic, have suffered from severe Chronic Neuropathic Pelvic Pain and multiple other co-morbidities.

My colleague, Elisabeth Oas, created this arena in which others can come and find resources, information and hope. It is our mission to help educate the patient on how to best get a complete diagnosis, more effective treatment, and eventually have a better quality of life. Please refer to www.elisabethoas.com/pelvicfreedom for more info. You may also visit my blog at: http://fighting-pne.blogspot.com for my personal story.

The guest is Prof. dr. Jan M. Keppel Hesselink, MD, MS, PhD, of the Institute for Neuropathic Pain in The Netherlands.

http://www.blogtalkradio.com/pelvicmessenger/2012/03/01/the-pelvic-messenger-welcome  

Magnesium stearate is widely used as an excipient in supplements, dietfood for medical purposes and drugs, because machines compressing tablets run more smooth if magnesium starate is added to tablets. Basically this thus has nothing to do with our body but all with the industriel proces of making tablets. We will give an example of two supplements, and bring arguments why one should chose the supplement devoid of magnesium stearate.

Magnesium stearate is the base of the Normast tablets, and many people have asked in the past why does Normast which contains the natural and body-own protective fatty compound palmitoylethanolamide, also contains such an unatural fat as magnesium stearate?

In the table both supplements are compared. Normast contains magnesium stearate and a number of other excipients which have no use of the organism, but are only put in based for pharmaceutical and technical reasons for instance, to be able to press tablets more quickly. Therefore the purity of palmitoylethanolamide in each tablet or capsule is 30% lower in Normast compared to PeaPure, which does not contain any excipients. But now the science why magnesium stearate is not such a good idea in foodsupplements.

Normast ist seit November 2012 in den Niederlanden nicht mehr verfügbar. Normast in den Niederlanden wird durch PeaPure ersetzt.

Die Wirkung von Palmitoylethanolamid entfaltet sich durch natürliche Mechanismen des Körpers. Nach der Einnahme kommt es zu zahlreichen biologischen Prozessen in den Zellen. Dadurch kann es einige Wochen dauern, bevor die Wirkung spürbar ist.  

PeaPure ist nach neuesten wissenschaftlichen Erkenntnissen entwickelt.

PeaPure enthält Palmitoylethanolamid, wie Normast. PeaPure wurde aber keinerlei chemischer Hilfsstoff, Geschmacksstoff, Farbstoff oder Süßstoff zugefügt. 
Dem Inhalt Normast sachets enthalt Sorbitol. 
Es gibt Nutzer, die diesen Süßstoff nicht einnehmen möchten. 
PeaPure-Kapseln enthalten kein Sorbitol, einzig und allein Palmitoylethanolamid.

PeaPure nimmt man am besten während oder nach der Mahlzeit ein. Es hat sich erwiesen, dass 3 Mal täglich 1 Kapsel à 400 mg eine gute Anfangsdosierung während der ersten 2 Monate ist.



Anwender van PeaPure spüren im Allgemeinen eine Verbesserung in den ersten Wochen der Einnahme. 
Erst nach zwei Monaten lässt sich die Wirkung von PeaPure wirklich beurteilen.

Palmitoylethanolamide  (PEA) is an anti-inflammatory body own molecule and might be able to fight off part of the neuro-inflammation in ALS. 

Simonetta Clemente (MD) from the Macomer Rehabilitation Center, Nuoro Health Care Center, Italy published an important mile stone paper in 2012, title: 'Amyotrophic Lateral Sclerosis Treatment with Ultramicronized Palmitoylethanolamide: A Case Report'.

In this paper she descibes the positive effect of the natural and body-own compound palmitoylethanolamide (PEA) in ALS, amyotrophic lateral sclerosis, a devasting neurological disorder also known as Lou Gehrig's disease in the USA.

In her article she points out that PEA has potent anti-inflammatory activity in many acute and inflammatory and chronic pain models, that PEA reduces spinal cord trauma in mice, and has neuroprotective properties.

She refers to the recent findings from professor's Cruccu's group, that PEA has seen to improve myelinated-fibre function in patients with chemotherapy-induced painful neuropathy and to other recent publications were PEA was seen to reduce pain severity in patients with pain associated to different pathological conditions who were undergoing standard therapies with unsatisfactory results or in those patients who discontinued standard therapy because of important side effects.

Given the lack of an effective therapy for ALS, as she correctly stated, she explored and reported the effects of PEA in a case of ALS.   

Back pain is common in both dogs and humans, and a new treatment without side effects based on the all natural painkiller palmitoylethanolamide  (PeaPure or Normast) is now available. PeaPure is available via a webshop in Europe and produced in the Netherlands according to GMP; Normast is available in Spain and Italy, and available in pharmacies. PeaPure is probably the best alternative for dogs, due to the absence of chemical fillers.

Back pain is often associated with intervertebral disc (IVD) degeneration.

Dr. Bergknut, N. wrote a PhD thesis on this topic, publihed in Acta Universitatis Agriculturae Sueciae, Volume: 2010, Issue: 91 (2011), from which we quote parts of the summary.

Horses often suffer from chronic pain states related to running, jumping or other movement- related disorders. Mostly either vetenarian analgesics or supplements are administered. The vetenarian analgesics have a clear drawback, namely various side effects, and most of the supplements are not scientifically well established as effective treatments.

Especially the use of corticosteroids and analgesics give rise to side effcts in horses wich can compromise their functions and quality of life. The body own analgesic and anti inflammatory agent palmitoylethanolamide can be succesfully applied to horses and horses suffering chronic pain and/ or inflammation. Many studies in various animals have proven the efficacy and safety of palmitoylethanolamide. The compound also has relevant efficacy in horses, as we will demonstrate in the following cases.

In nature animals have always been threatened by inflammation and pain. Inflammation and pain often go hand in hand. Often pain and inflammation are natural strategies of animals to survive: pain indicates and acts as an emergency signal, and inflammation kills bacteria and viruses.

However, there are types of pain and inflammation who are no good for survival. In man we know these states as auto-immune disorders, diseases such as rheumatoid artritis, inflammatory bowel disorder and the like.

In these cases the body itself attacks the tissues of the body itself, for no obvious reason at all. Inflammation without infection, without bacteria or viruses attacking our body we call aseptical inflammation. Chronic inflammation and pain are the base for a variety of disorders leading to unhappy horses. Some of these are: synovitis (inflammation joint membranes), artritis, tendinitis, colitis, skin hypersensitivity and eczema and many non-bacterial inflammations more.

Inflammation is a natural defence mechanism against tissue injury and usually leads to successful tissue healing. Sometimes, the inflammatory process itself actually causes further injury. In such circumstances it is appropriate to intervene with analgesic (pain-killing) and anti-inflammatory drugs. We will demonstrate the usefulness of a natural painkiller and anti-inflammatory compound, which is regarded as a breakthrough in the treatment of pain and inflammation.

An interesting new therapeutic approach for the rehabilitation and Amyotrophic Lateral Sclerosis hasl been presented in Milan, during the second day of the XII National Congress of SIRN, the Italian Society of Neurological Rehabilitation.

The new hope in the treatment of ALS, neuro-degenerative disease that affects about one in every 100 (mostly men of middle or advanced age), and in 5% of cases are familial, comes from "palmitoylethanolamide" (PEA).

It is an endogenous compound with anti-inflammatory effect cannabinergico, discovered years ago by Italian scientists in the group that included, among others, the Nobel Prize Professor Rita Levi Montalcini.

PEA for ALS: further information 

La cystite est un mot difficile pour une infection de la vessie. La cystite interstitielle est plus compliquée. Il s'agit d'une inflammation chronique de la vessie, où les bactéries ne jouent aucun rôle. On estime que plusieurs milliers de personnes dans notre pays souffrent de cette méchante maladie de la vessie, et la plupart d'entre eux sont des femmes. Avant de parler de la cystite interstitielle, le médecin traitant, un urologue ou un gynécologue doit être consulté afin d'exclure l'existence d'une infection ou un cancer. Ce sont les deux conditions qui causent le plus de problèmes et de douleurs en urinant.

Parce que  «la cystite interstitielle » est un terme difficile, nous utilisons plutôt le terme «syndrome douloureux de la vessie ». Ce terme recouvre exactement la charge: c’est douloureux, liés à la vessie et aucune maladie évidente mais un syndrome!

There is a new painkiller available in Germany and other European countries, based on a body own and all natural compound which proved to be effective and without any troublesome side effects, professor Jan M. Keppel Hesselink, pointed out at an important medical congres in Italy on November 24-26, 2011. Leading international pain experts, such as the German professor Ralph Baron also spoke at that congres. 

Keppel hesselink, holding a chair in molecular pharmacologist at the University of Witten/Herdecke in Germany, presented a major breakthrough in chronic pain treatment during the anual neurological congress for Italian anesthesiologists and painspecialists (SAARTI). While nearly all painkillers available inhibit pain via the nerve cells, Keppel Hesselink pointed out that a totally different and natural approach via the modulation of the so called glia cells has been overseen. The compound is available as the foodsupplement PeaPure  and as Normast .

Die Lyme Borreliose ist eine schwächende Erkrankung, die sich als chronischer Schmerz zeigen kann. Alle Gesundheitseinrichtungen müssen sich dem klinischen Wesen bewusst sein und müssen diese Infektionserkrankung in verschiedenen Diagnosen berücksichtigen.

Lyme Borreliose ist eine immer mehr verbreitete Infektionskrankheit. 90% aller vector-borne Erkankungen in den Vereinigten Staaten. Von nahezu 100,000 Fälle ist seit 1980 berichtet worden. Dies stellt eine 26fache Steigerung in der Periode von 1982 bis 1996 dar. Während 70% der Fälle im Nordosten auftreten, wird die LB aber auch im Norden und an der Pazifikküste gefunden.

Es muss angenommen werden, dass Kinder und Erwachsene während ihrer Aktivitäten in der Schule, am Arbeitsplatz und in der Freizeit einem Infektionsrisiko ausgesetzt sind. Durch die vielfältigen und bequemen Reisemöglichkeiten erscheint die Lyme Borreliose heute auch in Regionen, in denen sie nicht ursprünglich auftrat.

Es ist sehr wichtig, dass die Gesundheitseinrichtungen mir den ersten Anzeichen und Symptomen dieser Infektionserkrankung vertraut sind.Symptome, die mit der Lyme Borreliose in Verbindung gebracht werden, beinhalten Kopfschmerzen und chronische Schmerzen, die in der Gestalt verschiedener Pathologie und Störungen auftreten können. Patienten mit undeutlichen Beschwerden, nicht spezifischen Allgemeine, Gesichts- und Kopfschmerzen, mit einer Krankengeschichte, die verschiedene Systeme und Behandlungen umfasst, sind auf jeden Fall verdächtig. 

Un nouvel anti-inflammatoire et analgésique. Le produit est entièrement naturel. Il est facile à utiliser, y compris les effets chez les personnes âgées et d'autres médicaments et sans effets secondaires problématiques! Brandname: Normast ou PeaPure.

Était grand temps pour les patients souffrant de douleur chronique. Un analgésique nouvelle est vraiment nécessaire. Fin de l'année 2010 était arrivé: la palmitoyléthanolamide substance naturelle endogène (Normast) était disponible . Enfin, un analgésique nouvelle et naturelle, que pratiquement aucun des effets secondaires ou les interactions, et au moins aussi bonne, sinon plus efficace que les médicaments existants. PEA est disponible en deux types. Normast  et PeaPure  sont les deux marques.

Chronische Rückenschmerzen strahlen häufig auf den kompletten Bewegungsapparat aus. Dadurch ist die Lebensqualität stark eingeschränkt. Auch Ischias verursacht starke Schmerzen, die die Mobilität einschränken und die Freude am Leben vermindern. Bei Ischias, Neuralgieen und Bandscheibenvorfall sind die Nerven teilweise entzündet. Palmitoylethanolamin (Normast; PeaPure) ist ein effektives, natürliches Mittel gegen neuropathischen Schhmerzen, neuralgische Schmerzen, Rückenschmerzen und andere Schmerzen im Bewegungsapparat, Kiefer und Pelvis.

Normast ist seit November 2012 in den Niederlanden nicht mehr verfügbar. Normast in den Niederlanden wird durch PeaPure ersetzt. PeaPure ist nach neuesten wissenschaftlichen Erkenntnissen entwickelt.

PeaPure enthält Palmitoylethanolamid, wie Normast. PeaPure wurde keinerlei chemischer Hilfsstoff, Geschmacksstoff, Farbstoff oder Süßstoff zugefügt. 


Dem Inhalt Normast sachets enthalt Sorbitol.
Es gibt Nutzer, die diesen Süßstoff nicht einnehmen möchten. 
PeaPure-Kapseln enthalten kein Sorbitol, einzig und allein Palmitoylethanolamid. PeaPure nimmt man am besten während oder nach der Mahlzeit ein. Es hat sich erwiesen, dass 3 Mal täglich 1 Kapsel à 400 mg eine gute Anfangsdosierung während der ersten 2 Monate ist.

 Anwender van PeaPure spüren im Allgemeinen eine Verbesserung in den ersten Wochen der Einnahme.  Erst nach zwei Monaten lässt sich die Wirkung von PeaPure wirklich beurteilen.  

PeaPure enthält palmitoylethanolamin in einer einzigartigen Formulierung, die in einem patentierten Verfahren hergestellt wird. Es ist sehr magenfreundlich und Nebenwirkungen und Interactionen sind bisher nicht gemeldet..

PeaPure kann über einen längeren Zeitraum hinweg bei Rückenschmerzen und neuropathische Schmerzen ohne Probleme neben andere Medikamenten eingenommen werden. Hintergruende Hier.

Palmitoylethanolamide (PEA): more than 300 entries in pubmed for this interesting molecule.

At the Third International Congress on Neuropathic Pain, Athens, Greece, May 27 – 30, 2010 A. Biasiotta, S. et al presented a poster which demonstrated a clinical relevant and positive electrophysiological measurable effects from this rather unknown natural compound is internationally available as PeaPure, a dietsupplement. 

It demonstrated to be a good analgesic drug in a variety of painstates, with no troublesome side effects, neither drug-drug interactions. PeaPure contains only pure PEA, without chemical excipients/fllers.

This is very interesting for us, as PEA is an endogenious fatty acid and with properties comparable to anandaminde, as well as other endogenious cannabinoiuds. Lipids like N-palmitoylethanolamine can act as signaling molecules, activating intracellular and membrane-associated receptors to regulate physiological functions. The signaling lipid PEA is known to activate intracellular, nuclear and membrane-associated receptors and regulate many physiological functions related to the inflammatory cascade, and thus is of high interest in the treatment of neuropathic, or gliopathic pain.

Under this link all relevant scientific information. 

Rita Levi-Montalcini! 

Quand elle avait plus de quatre-vingt ans professeur Rita Levi-Montalcini, lauréate du prix Nobel de médecine, se mettait devant le microscope. Elle a décrit dans ces années, nous parlons début des années 90, une toute nouvelle façon de traiter la douleur et l'inflammation. Pas avec un agent inventé par les chimistes dans l'industrie pharmaceutique, mais avec une molécule que notre corps produit lui-même.  Palmitoylethanolamide (Normast, PeaPure).

Normast en Italie sur le marché et est fabriqué en Italie. PeaPure  est expédiée dans le monde entier et est fait aux Pays-Bas. 

Carpal Tunnel Syndrome (CTS) is the most common compression neuropathy. It is the reason for pain and functional impairment. On the picture we see in yellow the median nerve, being compressed under a ligament in the wrist. This gives rise to chronic pain. Pain normally can be reduced with oral neuropathic analgesics. However, the side effects of most of the NSAIDS limit its use.  It is available in its purest form as PeaPure , without chemical excipients.

Palmitoylethanolamide (PEA) , a fatty acid occuring naturally in our body, has also neuropathic pain reducing properties. Furthermore, it stabilizes mast cells, present in the carpal tunnel. Besides the pain reducing effect, PEA has also neuroprotective properties. To evaluate the clinical effects of PEA in CTS, Italian researchers randomised 28 diabetic patients with CTS, in two groups: one group received PEA twice daily 600mg and the other group received placebo.

PEA has been administered in clinical trials in around 2800 patients suffering from pain, and another 2000 suffering from the flu. 

In the traditional Bhutanese medicine the golden needle therapy is very popular. The golden needle is a nail like golden thick needle, used to treat many disorders. Many patients actively ask the traditional healer to be treated with the golden needle. The golden needle therapy is seen by many Bhutanese patients as something quite special.

IOCOB visited in 2008 a traditional healer to inquire about this method. We thougt the method might be related to Chinese medicine, were golden needles are used also. But it appeared to be quite different. Golden neelde therapy is cauterization: the  golden needle is heated and on certain points, unrelated to acupuncture points, the heated needle is applied. Not piercing through the skin, but only touching the skin. This it is not acupuncture, but cauterization. The therapy is a 2nd line therapy, if herbal remedies are not sufficient.

A Geranium species, Pelargonium (Pelargonium sidoides) is used in South Africa as a natural antibiotic. Its name is ‘Umckaloabo’, and it has been used for centuries by the Zulu, Basuto, Xhosa and Mfenfi tribes. It seems to be especially valued for its action on upper respiratory tract infections, coughs and ear, nose and throat infections as well for its ability to support rapid recovery from bronchitis, colds and flu.

In 1897 Charles Stevens, an Englishman, was treated with this geranium to cure him from tuberculosis. Fully recovered, he took this remedy to Europe and the herb gained in popularity since than. 

To date an impressive number of studies of Geraniumroot extract (Pelargonium sidoides) have been published so far. One, from Bulgaria, tested Geranium extract in the laboratory and documented its anti-viral activity. Another study, from Germany, published in the Journal of Family Practice in March 2004, found that Geranium reduced the severity as well as the duration of acute bronchitis. That study compared Geranium against placebo The evaluation was done in 476 men and women. The symptoms of bronchitis were evaluated on a scale used to measure the severity of that disease. After seven days of treatment, the patients who received the extract had better scores on the rating scale than did the patients who took the placebo. The efficacy and safety of the Geranium Pelergonium is sufficiently documented. One of the remaining questions is, would it be of use against the flu? 

Relaxation, the base of meditation and mindfulness. First you Relax, than you fall in meditation. You fall, as you can not steer the proces. You can only create an environment inwhich meditation occurs........